图书简介

Part 1: An overview of signalling; 1 Aspects of cellular signalling; 2 Pathways are the key to signalling; 3 A look at some of the history and techniques of cell signalling; Part 2: Components that comprise signalling pathways; 4 Extracellular signals: hormones, cytokines and growth factors; 5 Detection of extracellular signals: the role of receptors; 6 Protein phosphorylation, kinases and phosphatases; 7 Cyclic nucleotides, cyclases and G proteins; 8 Inositol phosphate metabolism and roles of membrane lipids; 9 Intracellular calcium ions: control of their concentrations and roles in signalling; 10 Reactive oxygen species, reactive nitrogen species and redox signalling; Part 3: Selected examples of signalling pathways and events; 11 Insulin and the signal transduction cascades it invokes; 12 Perception of the environment; 13 Signalling in development and for the regulation of gene expression; 14 Life, death and apoptosis; Part 4: Final thoughts; 15 Cell signalling: importance, complexity and the future

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