图书简介
Estrogens and Memory: Basic Research and Clinical Implications provides a compendium of cutting-edge basic and clinical research describing the ways in which estrogens regulate memory in a variety of species. Chapters are written by leading experts whose work is on the forefront of this exciting field. Three fundamental discussions focus on: effects of estrogens on the hippocampus and other brain regions central to memory, effects of estrogens on memory and related cognitive processes throughout the lifespan, and translational implications of estrogenic regulation of memory for aging and disease.
Contributors; Introduction; Karyn M. Frick; Part I Estrogen effects on the hippocampus and related brain regions; 1. Estrogen receptor distribution in the hippocampus and prefrontal cortex; Annelyn Torres-Reveron, Wayne G. Brake, and Teresa A. Milner; 2. Estrogen receptors at the membrane: Interactions with metabotropic glutamate receptors and caveolin proteins regulated through palmitoylation; Katherine R. Tonn, Paul G. Mermelstein, and John Meitzen; 3. Rapid effects of estradiol on dendritic spines and synaptic plasticity in the male and female hippocampus; Asami Kato, Gen Murakami, Yasushi Hojo, Sigeo Horie and Suguru Kawato; 4. Rapid modulation of spinogenesis by estradiol in the neocortex: An emerging role for GPER?; Deepak P. Srivastava, Katherine J. Sellers, Peter D. Evans; 5. Estrogenic regulation of synaptic actin proteins and plasticity; Eniko A. Kramar; 6. Hippocampal synaptic stability and plasticity: The role of hippocampus-derived estradiol; Gabriele M. Rune; 7. Estrogenic regulation of glia and neuroinflammation; Andrea Crespo-Castrillo, Maria Angeles Arevalo, Luis M. Garcia-Segura, and Natalia Yanguas-Casas; Part II Estrogenic regulation of memory and related cognitive processes throughout the lifespan; 8. Molecular mechanisms underlying rapid effects of estradiol on memory consolidation; Karyn M. Frick, Jaekyoon Kim, Wendy Koss, and Jennifer J. Tuscher; 9. Estrogenic regulation of spatial memory in songbirds; David J. Bailey and Colin J. Saldanha; 10. Estrogenic regulation of recognition memory and spinogenesis; Victoria N. Luine and Maya Frankfurt; 11. Who are you and what do you know? Estrogenic regulation of social recognition and social learning; Paul A.S. Shepard, Talya Kuun, Pietro Paletta, and Elena Choleris; 12. Estrogens have their ups and downs: A multiple memory systems approach to the bidirectional effects of estrogens on learning strategy; Donna L. Korol; 13. Puberty: Effects on the prefrontal cortex and cognitive behavior; Janice M. Juraska; 14. Ovarian hormones, cognition, and reproductive aging: Applications and implications for translating preclinical endocrine brain research to the clinic; Alesia A. Prakapenka, Veronica Pena, Heather A. Bimonte-Nelson; 15. Estrogenic regulation of hippocampal neurogenesis throughout the lifespan; Shunya Yagi, Rand Mahmoud, Wansu Qiu, Paula Duarte-Guterman, and Liisa A.M. Galea; 16. Effects of estradiol on basal forebrain cholinergic neurons and their impact on cognitive performance and age-related cognitive decline; Robert B. Gibbs; 17. Estrogenic regulation of synaptic health and cognition in aging rhesus monkeys; Johanna L. Crimins, Yuko Hara, John H. Morrison; Part III Translational implications of estrogenic regulation of memory for aging and disease; 18. Hormone therapy in postmenopausal women: The Women’s Health Initiative Memory Study and its continuing impact on research and practice; Ira Driscoll, Stephen R. Rapp, Karen C. Johnson, Mark A. Espeland; 19. Estrogen treatment in Alzheimer’s disease: Translational implications of estrogenic regulation of memory for aging and disease; Kelly N. Morgan and Carey E. Gleason; 20. Effects of dietary estrogens on dementia; Shelina Kassam, Mira Soni, Eef Hogervorst; 21. Oral contraceptive effects on cognition; Soniya Assudani Patel, Courtney McQuade, Robert S. Astur; 22. Effects of SERMS and antiestrogens on cognition in women with breast cancer; Jeffrey D. Blaustein; 23. Estrogen neuroprotection and anti-inflammation actions in the hippocampus; Roshni D. Thakkar, Ruimin Wang, Gangadhara R. Sareddy, Ratna K. Vadlamundi, and Darrell W. Brann; 24. Estrogenic regulation of neuroprotection and inflammation in ischemic stroke and aging; Farida Sohrabji, Shameena Bake, Amutha Selvamani; 25. Estradiol and fear generalization: Implications for anxiety disorders; Aaron M. Jasnow, Jordan M. Adkins, and Joseph F. Lynch III; 26. Role of estrogens in addiction-related learning; Hanna Yousuf; Part IV Conclusions and Future Directions; 27. Moving forward: A vision for future research on estrogenic regulation of memory; Karyn M. Frick; Index
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