图书简介

1 Drugs and Drug Targets; 2 Protein Structure and Function; 3 Enzymes: Structure and Function; 4 Receptors: Structure and Function; 5 Receptors and Signal Transduction; 6 Nucleic Acids: Structure and Function; 7 Enzymes as Drug Targets; 8 Receptors as Drug Targets; 9 Nucleic Acids as Drug Targets; 10 Miscellaneous Drug Targets; 11 Pharmacokinetics and Related Topics; Case Study 1 Statins; 12 Drug Discovery: Finding a Lead; 13 Drug Design: Optimizing Target Interactions; 14 Drug Design: Optimizing Access to the Target; 15 Getting the Drug to Market; Case Study 2 The Design of ACE Inhibitors; Case Study 3 Artemisinin and Related Antimalarial Drugs; Case Study 4 The Design of Oxamni; Case Study 5 Fosfidomycin as an Antimalarial Agent; 16 Combinatorial and Parallel Synthesis; 17 In Silico Drug Design; 18 Quantitative Structure-Activity Relationships; Case Study 6 De Novo Design of a Thymidylate Synthase Inhibitor; 19 Antibacterial Agents; 20 Antiviral Agents; 21 Anticancer Agents; 22 Protein Kinase Inhibitors as Anticancer Agents; 23 Antibodies and Other Biologics; 24 Cholinergics, Anticholinergics, and Anticholinestarases; 25 Drugs Acting on the Adrenergic Nervous System; 26 The Opioid Analgesics; 27 Anti-Ulcer Agents; 28 Cardiovascular Drugs; Case Study 7 Steroidal Anti-Inflammatory Agents; Case Study 8 Design of a Novel Antidepressant; Case Study 9 The Design and Development Of Aliskiren; Case Study 10 Factor Xa Inhibitors; Case Study 11 Reversible Inhibitors of HCV NS-34A Protease

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