图书简介
Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies. Addresses hematologic conditions including leukemia, lymphoma, and myeloma. Offers guidance on hematopoietic cell transplantation for solid tumors. Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications. Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT. Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference. Offers team-based, clinically-focused coverage from world-renowned leaders in the field. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Part One Introduction Ch 1 Evolution of HCT, past, present, and future Ch 2 Human leukocyte antigen Ch 3 Introduction and basic science of chimeric antigen receptor therapies Ch 4 Statistical methods in HCT and cellular therapies Part Two Methodology Ch 5 Hematopoietic cell collection; bone marrow harvesting, apheresis, UCB Ch 6 Leukapheresis and manufacturing of CAR cells Part Three General Clinical Aspects Ch 7 Patient and donor selection and preparing for HCT Ch 8 General management of patients undergoing HCT Ch 9 Haploidentical HCT Ch 10 Umbilical cord blood transplantation Ch 11 Process and general management of patients undergoing CAR therapies Part Four Pharmacology and Radiation Therapy Ch 12 Preparative regimens used in HCT and CAR therapies Ch 13 Pharmacology of drugs used in HCT and CAR therapies Ch 14 Role of radiation therapy in HCT and CAR therapies Part Five Disease-Specific Indications and Results Ch 15 HCT in AML Ch 16 CAR therapy in AML Ch 17 HCT in ALL Ch 18 CAR therapy in ALL Ch 19 HCT in chronic leukemias; CML and CLL Ch 20 HCT in MDS Ch 21 HCT in myeloproliferative disorders Ch 22 HCT in aplastic anemia Ch 23 HCT in multiple myeloma Ch 24 CAR therapy in multiple myeloma Ch 25 HCT in light-chain amyloidosis Ch 26 HCT in NHL Ch 27 HCT in Hodgkin lymphoma Ch 28 CAR therapy in lymphoma Ch 29 HCT in rare malignancies Ch 30 HCT for hematologic malignancies in HIV patients Ch 31 HCT in solid tumors Part Six Prevention and Management of Complications Ch 32 Infectious complications Ch 33 Graft failure Ch 34 Graft-versus-host disease Ch 35 Miscellaneous complications of HCT Ch 36 Cytokine release syndrome Ch 37 Neurologic complications of CAR therapy (ICANS) Ch 38 Miscellaneous complications of CAR therapy Ch 39 Symptoms management and palliative care Ch 40 Survivorship
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