图书简介
Thoroughly updated to reflect today’s recent advances in adult and pediatric endocrinology, DeGroot’s Endocrinology, 8th Edition, remains the comprehensive, international reference of choice for today’s endocrinologists and fellows. A full peer review of the previous edition, conducted by a largely new group of renowned editors, was used to update this trusted, two-volume resource. In-depth coverage of both basic and clinical aspects of endocrinology and up-to-date information on the treatment and management of endocrine disorders are provided by a diverse group of expert contributors from six continents. A full-color format and helpful algorithms summarize clinical decision-making and practical approaches to patient management. Organizes content by all the glands that regulate the endocrine system while integrating basic science and clinical presentations of disease. Includes new chapters: Anatomy and Physiology of the Hypothalmus and Pituitary, Differentiated Thyroid Cancer, Medullary Thyroid Cancer, Drugs that Affect Thyroid Function, Genetic Disorders of the Adrenal Cortex, Adrenal Pathology, Primary Aldosteronism, Transgender Healthcare, Erectile Dysfunction, Prevalence and Causes of Male Infertility, Sexual Dysfunction in the Female, Glucose Toxicity and Oxidative Stress. Emphasizes basic science and evidence-based practice throughout. Features extensive updates to content on thyroid and adrenal disfunction, endocrine-disrupting chemicals and human disease, clinical management of diabetes, and advances in genetics. Includes algorithms to outline effective treatment protocols. Contains new emphasis boxes that highlight key points in each chapter. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1 Principles of Endocrinology 2 Regulation of Islet Hormone Synthesis and Secretion 2 Principles of Endocrine Measurements 3 Applications of Genetics in Endocrinology 3 Endocrine-Disrupting Chemicals and Human Disease 3 Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks 4 Prolactinomas and Disorders of Prolactin Secretion 5 Hypopituitarism including Growth Hormone Deficiency 6 Acromegaly 7 Development of the Pituitary 7 Cushing’s Disease 8 CLINICALLY NONFUNCTIONING SELLAR MASSES 9 TSH-Producing Pituitary Tumors 10 Pituitary Surgery 11 CRANIOPHARYNGIOMAS AND PARASELLAR MASSES 12 DISORDERS OF SODIUM, DIABETES INSIPIDUS AND HYPONATRAEMIA 13 Anatomy and Physiology of the Hypothalmus and Pituitary 14 Genetic Disorders of the Pituitary 15 Aggressive Pituitary Tumors 16 Radiotherapy in Pituitary Tumors 17 Somatic Growth and Maturation: Growth hormone and Other Growth Factors 18 Growth Hormone Deficiency in Children 19 Basic and Clinical Aspects of Appetite Regulation and Energy Expenditure 20 Obesity: Risk, Risk Factors, and Medical Management 21 GENETIC OBESITY SYNDROMES 22 Regulation of Intermediary Metabolism During Fasting, Feeding, and Exercise 23 Adipose Tissue Function: Metabolic and Endocrine 24 Lipodystrpohy Syndromes 25 Lipoprotein Metabolism and the Treatment of Lipid Disorders 26 Metabolic Syndrome 27 Bariatric Procedures and Operations 28 Development of the Endocrine Pancreas 29 Regulation of Islet Hormone Synthesis and Secretion 30 Mechanisms of Insulin Action 31 Classification and Diagnosis of Diabetes Mellitus 32 Autoimmune (Type 1)Diabetes Mellitus: Etiology, Pathogenesis, Prediction, and Prevention 33 Type 2 Diabetes Mellitus: Etiology, Pathogenesis, and Natural History 34 Diabetes Mellitus and Pregnancy 35 Hyperglycemia Secondary to Non-Traditional Diabetic Conditions and Therapies 36 Beta-cell Glucose Toxicity and Oxidative Stress 37 DIABETIC KETOACIDOSIS AND HYPERGLYCEMIC HYPEROSMOLAR STATE 38 Hypoglycemia and Hypoglycemic Syndromes 39 Treatment of Type 1 Diabetes Mellitus in Adults 40 Clinical Management of Type 2 Diabetes Mellitus 41 Pancreas and Islet Transplantation 42 Diabetes and Long-Term Complications 43 Diabetic Eye Disease 44 Diabetic Neuropathy 45 Glucose Sensors and Insulin Pumps 45 Diabetic Kidney Disease 46 Diabetic Foot and Vascular Complications 47 Parathyroid Hormone and the Parathyroid Hormone Receptor Type 1 in the Regulation of Calcium and Phosphate Homeostasis and Bone Metabolism 48 Parathyroid Hormone-Related Protein 49 Calcitonin 50 Vitamin D: From Photosynthesis, Metabolism, and Action to Clinical Applications 51 Bone Development and Remodeling 52 Regulation of Calcium Homeostasis and Genetic Disorders that Affect Calcium Metabolism 53 Genetic Disorders of Phosphate Homeostasis 54 Primary Hyperparathyroidism 55 Hypercalcemia of Malignancy 56 Surgical Management of Hyperparathyroidism 57 PSEUDOHYPOPARATHYROIDISM, ALBRIGHT’S HEREDITARY OSTEODYSTROPHY, AND PROGRESSIVE OSSEOUS HETEROPLASIA: DISORDERS CAUSED BY GNAS MUTATIONS THAT REDUCE Gsa ACTIVITY 58 Genetic Defects in Vitamin D Metabolism and Action 59 Hereditary Disorders of the Skeleton 60 Osteoporosis 61 CKD-MBD Syndrome: Chronic Kidney Disease Produced Disorders in Skeletal, Vascular, and Cardiac Tissues and Mineral Metabolism 62 Disorders of Mineralization 63 Paget’s Disease of Bone 64 Anatomy and Development of the Thyroid 65 Thyroid-Stimulating Hormone and TSH Receptor 66 Thyroid Hormone Transporters and Metabolism 67 Thyroid Hormone Action 68 Thyroid Function Testing (TSH, T3, and T4) 69 Thyroid Imaging 70 Pathology of the Thyroid Gland 71 Graves’ Disease 72 Graves’ Orbitopathy 73 Thyroiditis 74 Hypothyroidism 75 Thyroid and Pregnancy 76 Iodine Nutrition and the Thyroid 77 Euthyroid and hyperthyroid nodules and goiter 78 Differentiated Thyroid Cancer - Streamlining Diagnosis And Optimizing Management 79 Medullary Thyroid Cancer 80 Anaplastic (Undifferentiated) Thyroid Carcinoma 81 RESISTANCE TO THYROID HORMONE
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