图书简介

Cell-penetrating peptides.- Shuttling homeoproteins and their biological significance.- Artificial evolutionary optimization process to improve the functionality of CPPs.- In silico design of chemically modified cell penetrating peptides.- Synthetic Molecular Evolution of Cell Penetrating Peptides.- A native CPP from rattlesnake with therapeutic and theranostic properties.- Synthesis of cell-penetrating peptide coated silica nanoparticles and their physicochemical and biological characterization.- Enhancing the therapeutic potential of extracellular vesicles using peptide technology.- Challenges and methods for the study of CPP translocation mechanisms.- Membrane molecular interactions and induced structures of CPPs.- A single GUV method for revealing the action of cell-penetrating peptides in biomembranes.- Methods for Small-Angle Scattering Measurements on Peptiplexes of DNA with Cell-Penetrating Peptides.- Imaging CPP delivery mechanisms of oligonucleotides.- Quantitative subcellular analysis of cyclic cell-penetrating peptide EJP18 in non-adherent cells.- PepFect14: signaling and transfection.- Utilisation of cell-penetrating peptides for in vivo delivery of bioactive cargo – the effect of nanoparticle formulation.- Protein delivery by PTDs/CPPs.- Protein Delivery to Cytosol by Cell-Penetrating Peptide Bearing a Tandem Repeat Penetration-Accelerating Sequence.- Recombinant transcription factors (TFs) fused to ZEBRA minimal transduction domain (MD) for modulation of mRNA transcripts.- Protein mimicry and the design of bioactive cell penetrating peptides: The genesis of STOPSPERM bioportides.- Lipopeptide pepducins as therapeutic agents.- Delivery of Antibiotics by Cell-Penetrating Peptides to Kill Intracellular Pathogens.- CPP applications in immune modulation and disease therapy.- Cell-penetrating peptides as carriers for transepithelial drug delivery.- New tools for streamlined in vivo homing peptide identification.- Tumor targeting as new therapeutic approach.- Mitochondrial Targeting Probes, drug conjugates and gene therapeutics.- Novel brain penetrating single chain antibodies directed against 3RTau for the Treatment of Alzheimer’s Disease and related Dementias.- Strategies for peptide-mediated cargo delivery to human smooth muscle cells.- Tips and Tools to Understand Direct Membrane Translocation of siRNA-Loaded WRAP-Based Nanoparticles.- Evaluating efficacy of peptide-delivered oligonucleotides using the severe Taiwanese SMA mouse model.- Development of CPP-based methods for delivery of miRNAs into the skin and airways - lessons from cell culture and mouse models.- Endpoint and kinetic approaches for assessing transfection efficacy in mammalian cell culture.- Tissue analysis of lung-targeted delivery of siRNA and plasmid DNA.- Improvement of transfection with PepFects by organic and inorganic components.- DNA Transfer into Animal Cells Using Stearylated CPP Based Transfection Reagent.- Use of PepFect14 and siRNA for targeted gene silencing in human embryonic stem cells.- CRISPR/Cas9 plasmid delivery through the CPP: PepFect14.- Applications of CPPs in genome editing of plants.- Live Cell Genomics: Cell-specific transcriptome capture and exon-specific RNA binding protein isolation in live tissues and cells.

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