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Preface; Contributors; Section 1 - Clinical syndromes: General; 1 Fever of unknown origin; Cheston B. Cunha and Burke A. Cunha; 2 Sepsis; Leeja Joseph and Rodger D. MacArthur; ; 3 Chronic fatigue syndrome; Stephen J. Gluckman; Section 2 - Clinical syndromes: Head and neck; 4 Pharyngotonsillitis; Itzhak Brook; ; 5 Infectious thyroiditis; Jeanne Carey and Stephen G. Baum; 6 Otitis; Stephen I. Pelton; 7 Sinusitis; Rachel Kominsky and Todd Otteson; 8 Dental infections; Jessica Moskovitz, Bridget Hathaway, Jennifer Rubin Grandis, and Jonas T. Johnson; 9 Salivary and lacrimal gland infections; Alexandre Malek, Johny Fares, and Issam Raad; 10 Deep neck infections; Jeremy D. Gradon; Section 3 - Clinical syndromes: Eye; 11 Conjunctivitis; Elmer Y. Tu; ; 12 Keratitis; Elmer Y. Tu, Francis S. Mah, and Jules Baum; ; 13 Iritis; Alice Lorch and Ann-Marie Lobo; ; 14 Retinitis; Hillary C. Stiefel and Daniel M. Albert; 15 Endophthalmitis; Roy D. Brod, Harry W. Flynn, Jr., and Lili G. Kaplan; 16 Periocular/Retro-orbital infections; Miriam Barshak and Marlene L. Durand; Section 4 - Clinical syndromes: Skin and lymph nodes; 17 Fever and rash; John W. Sensacovic and Leon G. Smith; ; 18 Toxic shock syndrome and Kawasaki disease; Evangelia M. Assimacopoulos, Aristides P. Assimacopoulos, Wilmara Salgado-Pabon, and Patrick M. Schlievert; 19 Viral exanthems; Romina Bromberg, Michael Thompson, Lisa M. Chirch, and Jane M. Grant-Kels; 20 Skin ulcers; Joanne T. Maffei; ; 21 Cellulitis and erysipelas; Katherine S. Glaser and Kenneth J. Tomecki; 22 Deep soft-tissue infection: Necrotizing fasciitis and gas gangrene; Stephen Ash and Louis E. Kennedy; 23 Human and animal bites; Ellie J. C. Goldstein and F. Abrahamian; 24 Lice, scabies, and myiasis; Charlotte Bernigaud, Gentiane Monsel, and Olivier Chosidow; 25 Tungiasis and bed bugs; Tania F. Cestari and Simone Pessato; 26 Superficial fungal infection of skin and nails; Evelyn K. Koestenblatt and Jeffrey M. Weinberg; 27 Eumycetoma; Ncoza C. Dlova, Anisa Mosam, and Antoinette Chateau; 28 Lymphadenopathy/Lymphadenitis; Gerald Friedland and Sheela Shenoi; Section 5 - Clinical syndromes: Respiratory tract; 29 Bronchitis; Phillippa Poole and Mark Hobbs; 30 Croup, supraglottitis, and laryngitis; Irmgrad Behlau; 31 Atypical pneumonia; Thomas M. File, Jr.; 32 Community-acquired pneumonia; Keyur S. Vyas; 33 Nosocomial pneumonia; Cheston B. Cunha and Burke A. Cunha; 34 Aspiration pneumonia; Jean Gibb and Matthew Bidwell Goetz; 35 Lung abscess; Amee Patrawalla and Lisa L. Dever; 36 Empyema and bronchopleural fistula; Charlotte E. Bolton and Dennis J. Shale; Section 6 - Clinical syndromes: Heart and blood vessels; 37 Endocarditis; John L. Brusch; 38 Acute pericarditis; Richard A. Martinello and Michael Cappello; 39 Myocarditis; Lori Blauwet and Andrew Rosenbaum; 40 Mediastinitis; Ravi Karra and Keith S. Kaye; 41 Vascular infection; Susan E. Beekmann and David K. Henderson; 42 Infections of cardiovascular implantable devices; M. Rizwan Sohail, Daniel C. DeSimone, and James M. Steckelberg; Section 7 - Clinical syndromes: Gastrointestinal tract, liver, and abdomen; ; 43 Acute viral hepatitis; Kalyan Ram Bhamidimarri and Paul Martin; 44 Chronic viral hepatitis; Michelle E. Freshman and Lawrence S. Friedman; 45 Biliary infection: Cholecystitis, cholangitis; Raghav Chandra and Robert V. Rege; 46 Pyogenic liver abscess; Patricia Wong and H. Franklin Herlong; 47 Infectious complications in acute pancreatitis; Jodie A. Barkin and Jamie S. Barkin; 48 Esophageal infections; Uni Wong and Jean-Pierre Raufman; 49 Gastroenteritis; Douglas R. Morgan, Vivian Chidi, and Robert L. Owen; 50 Food poisoning; Carly R. Davis and Andrew T. Pavia; 51 Clostridioides (Clostridium) difficile; Cheston B. Cunha and Burke A. Cunha; 52 Sexually transmitted enteric infections; Thomas C. Quinn; 53 Acute appendicitis; Bian Wu and John Maa; 54 Diverticulitis; Matthew D. Zelhart and Ronald L. Nichols; 55 Abdominal abscess; K. Shad Pharaon and Donald D. Trunkey; 56 Splenic abscess; Walter Dehority and Thomas R. Howdieshell; 57 Peritonitis; Linda A. Slavoski and Matthew E. Levison; 58 Whipple’s disease and sprue; Amirkaveh Mojtahed and Payam Afshar; Section 8 - Clinical syndromes: Genitourinary tract; 59 Urethritis and dysuria; George Pappas, Ioannis A. Bliziotis, and Matthew E. Falagas; 60 Vaginitis and cervicitis; Sebastian Faro; 61 Epididymo-orchitis; Rebecca Fallis and Daniel Mueller; 62 Genital ulcer adenopathy syndrome; Allan Ronald; 63 Prostatitis; Cheston B. Cunha and Burke A. Cunha; 64 Pelvic inflammatory disease; William J. Ledger; 65 Urinary tract infection; Peter Liu, Keith W. Hamilton, and Judith A. O’Donnell; 66 Candiduria; Jack D. Sobel; 67 Focal renal infections and papillary necrosis; Ann F. Fisher and Louise M. Dembry; Section 9 - Clinical syndromes: Musculoskeletal system; 68 Infection of native and prosthetic joints; Shahbaz Hasan and James W. Smith; 69 Bursitis; Richard H. Parker; 70 Acute and chronic osteomyelitis; Ilona Kronig, Pierre Vaudaux, Domizio Suva, Daniel Lew, and Ilker Uckay; 71 Polyarthritis; Kathryn H. Dao and John J. Cush; 72 Infectious polymyositis; Shanthi Kappagoda and Upinder Singh; 73 Iliopsoas abscess; Larson Erb and Pamela A. Lipsett; Section 10 - Clinical syndromes: Neurologic system; ; 74 Bacterial meningitis; Jennie E. Johnson and Allan R. Tunkel; 75 Aseptic meningitis; Burt R. Meyers and Dalilah Restrepo; 76 Viral encephalitis; John J. Halperin and David N. Irani; 77 Intracranial suppuration; Brian Wispelwey and Christopher J. Arnold; 78 Spinal epidural abscess; Mark J. DiNubile; 79 Myelitis and peripheral neuropathy; Rohini Samudralwar and Rodrigo Hasbun; 80 Reye syndrome; Debra L. Weiner and Amy Kritzer; 81 Progressive multifocal leukoencephalopathy; Christopher M. Perrone and Joseph R. Berger; 82 Cerebrospinal fluid shunt infection; Elisabeth E. Adderson and Patricia M. Flynn; Section 11 - The susceptible host; 83 Evaluation of suspected immunodeficiency; Thomas A. Fleisher and Sergio D. Rosenzweig; 84 Infection in the neutropenic patient; Eric Holaday, Aaron Mishkin, and Rafik Samuel; 85 Infections in patients with neoplastic disease; Amar Safdar and Donald Armstrong; 86 Corticosteroids, cytotoxic agents; Babafemi Taiwo and Hannah Nam; 87 Biologics; Rebecca A. Ward, Pritha Sen, and Jatin M. Vyas; 88 Infection in transplant patients; Raymund R. Razonable; 89 Diabetes and infection; Sylvia J. Shaw and Raza Iqbal; 90 Infectious complications in the injection and non-injection drug user; Carlo Contoreggi; 91 Infection in the alcoholic; Laurel C. Preheim and Manasa Velagapudi; 92 Infection in the elderly; Kent Crossley; 93 Neonatal infection; Patrick G. Gallagher and Robert S. Baltimore; 94 Pregnancy and the puerperium: Infectious risks; Raul E. Isturiz and Jorge Murillo; 95 Dialysis-related infection; Peter Mariuz; 96 Asplenia; Larry I. Lutwick; Section 12 - HIV; 97 HIV infection: Initial evaluation and monitoring; Aaron E. Glatt, Andrea Sciberras, and Steven M. Weiss; 98 HIV: Antiretroviral therapy; Amy L. Brotherton and Joseph M. Garland; 99 Immune reconstitution inflammatory syndrome; Suzaan Marais and Graeme Meintjes; 100 Opportunistic infections in HIV; Marshall Glesby and Anthony Ogedegbe; 101 Prophylaxis of opportunistic infections in HIV disease; Brandi Manning, Robert L. Bettiker, and Jeffrey M. Jacobson; Section 13 - Nosocomial infection; 102 Percutaneous injury: Risks and management; David Kuhar and Krista Powell; 103 Hospital-acquired fever; Arthur E. Brown and Susan K. Seo; 104 Transfusion-related infection; William R. Jarvis and Virginia R. Roth; 105 Intravascular catheter-related infection; Johny Fares, Alexandre Malek, and Issam Raad; 106 Infections associated with urinary catheters; Lindsay E. Nicolle; Section 14 - Infections related to surgery and trauma; 107 Postoperative wound infection; E. Patchen Dellinger; 108 Trauma-related infection; Mark A. Malangoni; 109 Infected implants; Gordon Dickinson; 110 Infection in the burn-injured patient; Roger W. Yurt and Rafael Gerardo Magana; Section 15 - Prevention of infection; 111 Nonsurgical antimicrobial prophylaxis; Nadine Rouphael and Alexandra Wolcott Dretler; 112 Surgical prophylaxis; Sonya Trinh and George Pankey; 113 Immunizations; Elaine C. Jong; Section 16 - Travel and recreation; 114 Advice for travelers; Henry M. Wu and Jessica K. Fairley; 115 Fever in the returning traveler; Alimuddin Zumla; 116 Systemic infection from animals; David J. Weber, Jonathan J. Juliano, and William A. Rutala; 117 Tick-borne disease; Steven C. Buckingham; 118 Recreational water exposure; Mary E. Wilson and Andrea K. Boggild; 119 Travelers’ diarrhea; Karen J. Vigil and Herbert L. DuPont; Section 17 - Bioterrorism; 120 Bioterrorism; Megan Gallagher and Andrew W. Artenstein; Section 18 - Specific organisms: Bacteria; ; 121 Actinomycosis; Thomas A. Russo and Grishma R. Trivedi; 122 Anaerobic infections; Itzhak Brook; 123 Anthrax; Tirdad T. Zangeneh, Marc Traeger, and Stephen A. Klotz; 124 Bartonella bacilliformis; Nuria Sanchez Clemente; 125 Cat scratch disease and other Bartonella infections; William A. Schwartzman; 126 Bordetella; Emily Souder and Sarah S. Long; 127 Branhamella-Moraxella; Lisa S. Hodges and Joseph A. Bocchini, Jr.; 128 Brucellosis; Carlo Carrillo and Eduardo Gotuzzo; 129 Campylobacter; David W. K. Acheson; 130 Clostridium; Derek Forster; 131 Corynebacteria; Carlos H. Ramirez-Ronda and Carlos R. Ramirez-Ramirez; 132 Enterobacteriaceae; Charles Stratton; 133 Enterococcus; Ronald N. Jones and Rodrigo Mendes; 134 Erysipelothrix; W. Lee Hand; 135 HACEK; Vivian H. Chu; 136 Helicobacter pylori; David Y. Graham and Emiko Rimbara; 137 Neisseria gonorrhoea; Amy J. Mathers and Michael F. Rein; 138 Haemophilus; Amy Spallone and Daniel Musher; 139 Legionellosis; Thomas J. Marrie, Shelly McNeil, and Mark Robbins; 140 Leprosy; Bahir H. Chamseddin and Travis Vandergriff; 141 Meningococcus and miscellaneous neisseriae; Chuen-Yen Lau and Edmund C. Tramont; 142 Listeria; Bennett Lorber; 143 Nocardia; Lisa Haglund; 144 Pasteurella multocida; Andrew S. Webster, Paulina A. Rebolledo, Naasha J. Talati, and David S. Stephens; 145 Pneumococcus; Maurice A. Mufson and Nancy B. Norton; 146 Pseudomonas, stenotrophomonas, and burkholderia; Titus Daniels; 147 Rat-bite fevers; Neil S. Lipman; 148 Salmonella; Bruce S. Ribner; 149 Staphylococcus; Suzanne F. Bradley; 150 Streptococcus groups A, B, C, D, and G; Dennis L. Stevens, J. Anthony Mebane, and Karl Madaras-Kelly; 151 Viridans streptococci; John L. Brusch; 152 Poststreptococcal immunologic complications; Barbara W. Stechenberg; 153 Shigella; Eduardo Rodriguez-Noriega; 154 Tularemia; Kari Neeman and Jessica Snowden; 155 Tuberculosis; Jay B. Mehta and Asim K. Dutt; 156 Nontuberculous mycobacteria; Timothy Aksamit and David E. Griffith; 157 Vibrio; Duc J. Vugia; 158 Yersinia; Royce H. Johnson and Arash Heidari; 159 Miscellaneous gram-positive organisms; Iqra Choudary, Steven K. Schmitt, and Roberto Baun Corales; 160 Miscellaneous gram-negative organisms; Sampath Kumar and Kamaljit Singh; Section 19 - Specific organisms: Spirochetes; 161 Syphilis and other treponematoses; Arlene C. Sena and Adaora A. Adimora; 162 Lyme disease; Janine Evans; 163 Borreliosis; Sally Cutler; 164 Leptospirosis; Daniela Dimarco; Section 20 - Specific organisms: Mycoplasma and Chlamydia; ; 165 Mycoplasma; Ken B. Waites and Sixto Leal; 166 Chlamydia pneumonia; Margaret R. Hammerschlag; 167 Chlamydia psittaci (psittacosis); Thomas Marrie; Section 21 - Specific organisms: Rickettsia, Ehrlichia, and Anaplasma; 168 Rickettsial infections; Noah Wald-Dickler and Paul D. Holtom; 169 Ehrlichiosis and anaplasmosis; Johan S. Bakken and J. Stephen Dumler; Section 22 - Specific organisms: Fungi; 170 Candidiasis; Christopher F. Carpenter and Nicholas Gilpin; 171 Aspergillus; Stuart M. Levitz and Sanjay Ram; 172 Mucormycosis (and entomophthoramycosis); Scott F. Davies; 173 Sporotrichum; Robert A. Greenfield; 174 Cryptococcus; William G. Powderly; 175 Histoplasmosis; Cole Beeler and Mitchell Goldman; 176 Blastomycosis; Todd P. McCarty and Peter G. Pappas; 177 Coccidioidomycosis; Trung T. Vu, Jose Cadena, and Gregory M. Anstead; 178 Pneumocystis jiroveci (carinii); Shelley A. Gilroy and Nicholas Bennett; 179 Miscellaneous (emerging) fungi and algae; Obinna N. Nnedu and George A. Pankey; Section 23 - Specific organisms: Viruses; 180 Cytomegalovirus; Rima I. El-Herte and Jeffrey L. Meier; 181 Dengue; Nguyen Thanh Hung; 182 Enteroviruses; Penelope Dennehy; 183 Epstein-Barr virus and other causes of the infectious mononucleosis syndrome; Jeffrey L. Meier; 184 Hantavirus cardiopulmonary syndrome; Gregory Mertz; 185 Herpes simplex 1 and 2; Richard J. Whitley and Abdulsalam Alsulami; 186 Human herpes virus 6, 7, 8; Eleni Magira; 187 Influenza; Harvey M. Friedman and Ramin Herati; 188 Coronavirus-19; Smitha Gudipati, Gina Maki, Marcus Zervos, and Mayur Ramesh; 189 Papillomavirus in oro-genital infection; Lawrence J. Eron; 190 Acute and chronic parvovirus infection; Neal S. Young; 191 Rabies; Anita Mahadevan, Susarla K. Shankar, and Avindra Nath; 192 Varicella-zoster virus; Jeffrey M. Weinberg; 193 Viral hemorrhagic fevers; Daniel G. Bausch; Section 24 - Specific organisms: Parasites; 194 Intestinal roundworms; Kathryn N. Suh, Anne E. McCarthy, and Jay S. Keystone; 195 Tissue nematodes; Ian Michelow and Dan Blatt; 196 Schistosomes and other trematodes; James H. Maguire; 197 Tapeworms (cestodes); Zbigniew S. Pawlowski; 198 Toxoplasma; Roderick Go and Benjamin J. Luft; 199 Malaria; Jessica K. Fairley and Henry M. Wu; 200 Babesiosis; Tempe K. Chen, Choukri Ben Mamoun, and Peter J. Krause; 201 Trypanosomes and leishmania; Richard Pearson, Selma Jeronimo, and Anastacio de Sousa; 202 Intestinal protozoa; M. Paul Kelly; 203 Extraintestinal amoebic infection; Rosa Andrade; Section 25 - Antimicrobial therapy: General considerations; 204 Principles of antibiotic therapy; John S. Czachor; 205 Antibacterial agents; Richard Watkins; 206 Principles and practice of antimicrobial stewardship; Cheston B. Cunha; 207 Antifungal therapy; Dimitrios Farmakiotis and Ralph Rogers; 208 Antiviral therapy; Rajeev Shah and Cheston B. Cunha; 209 Probiotics; Varsha Gupta and Ritu Garg; 210 Hypersensitivity to antibiotics; Santiago Alvarez-Arango and N. Franklin Adkinson, Jr.; 211 Antimicrobial agent tables; Diane Parente and Cheston B. Cunha; Index $ MJCJ; MBNS; MJ; MJCM $ Infectious

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