图书简介
The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features:Reveals novel nanoscale approaches, toxicity assessment, and biomedical applicationsIncludes importance of nanotoxicity concepts in developing smart nanomaterialsHighlights unique contributions and "A to Z" aspects on the state-of-the-art from global leadersOffers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicinesNanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Furt
Chapter 1 Nanomaterials: Types of Nanomaterials and Their Fundamental Physicochemical Properties....................................... 1 A. Shubha, S. R. Manohara, and S. S. Subhranshu Chapter 2 Innovations in Nanotechnology for Biomedical Sensing, Imaging, Drug Delivery, and Therapy........................................... 21 Anine Crous and Heidi Abrahamse Chapter 3 Nanomaterials for Drug Delivery.................................................. 43 Shailja Jain, Srividya Gorantla, and Gautam Singhvi Chapter 4 PLGA-Based Nanoparticulate Systems: New Trends in Nanomedicine................................................................................ 73 Devendra Jain, Abhijeet Singh, Bjorn John Stephen, Suman Sanadhya, Hemant Kumar Daima, Harishkumar Madhyastha, and Radha Madhyastha Chapter 5 Employing New Targeted Nanoencapsulation for Alzheimer’s Disease Treatment: A Change for the Better?........... 97 Arti Devi and Zaved Ahmed Khan Chapter 6 Nanomaterials-Assisted Elicitation of Pharmaceutically Important Secondary Metabolites from In Vitro Plant Cell Cultures...........................................................117 Sekhar Tiwari, Sachin Kumar Verma, Abhishek Bhargava, Anusha Ebenezer Alpheus, Rasanpreet Kaur, Rajesh Sharma, and Neeraj Khare Chapter 7 Impact of Nanomaterials on Health and Environment................ 133 Faisal Ali, Kanwal Akhtar, Ahmed Nawaz, M. Munir Sajid, Naveed Akhtar Shad, Muhammad Abdul Qayyum, and Yasir Javed Chapter 8 Consequences of Nanomaterials on Human Health and Ecosystem.................................................................. 157 Priyanka Kumari, Richa Seth, and Abha Meena Chapter 9 Conceptual Understanding of the Mechanisms of Nanotoxicity and Safety of Nanomedicines................................. 201 Rotimi Damilare, Maimako Rotdelmwa, Ashonibare Victory, Ogunnupebi Temitope, and Adeyemi Oluyomi Stephen Chapter 10 Insights into the Mechanisms of Nanotoxicity and Evaluation of Nanomaterials........................................................ 225 Vinod Kumar Yata Chapter 11 Sensors to Monitor and Evaluate the Toxicity of Nanomedicine Applications......................................................... 245 Bambang Kuswandi Chapter 12 Systems Approaches for Toxicological Assessment of Nanomaterials...................................................... 277 Hasmik Yepiskoposyan, Marja Talikka, Vincenzo Belcastro, Nikolai V. Ivanov, Diego Marescotti, Manuel C. Peitsch, and Julia Hoeng Chapter 13 Measurement of Oxygen Consumption Rate Based on Fluorescence Intensity and Lifetime as a Strategy to Assess Nanotoxicity................................................................................. 303 T. Sushma, Hemant Kumar Daima, D. R. Ramesh Babu, S. Amutha, and Sangly P. Srinivas Chapter 14 Current Knowledge on Toxicity of Nanomaterials: Toxicity Assessment and Impact.................................................. 339 Bhaskar Das, Mayuri Chabukdhara, Sanjukta Patra, and Manashjit Gogoi Chapter 15 The Role of Nanotechnology in the Management of Water Toxicity.............................................................................. 377 Vinod Kumar Yata Chapter 16 Challenges in the Assessment of Nanotoxicity, Recommendations, and Safe-by-Design Nanomedicines to Counter Toxicological Problems.................................................. 393 G. V. S. Subbaroy Sarma, Manoj Kumar Enamala, Maria P. Nikolova, Murthy Chavali, and Sudhakar Reddy Pamanji Chapter 17 Current Guidelines and Regulatory Challenges, Insight into the Legal, Societal, and Ethical Issues of Nanomaterials............ 445 Harjeet Nath, S. S. Subhranshu, and S. R. Manohara
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