图书简介
Electrons are involved in all electrical phenomena, and living cells cannot be an exception. This book takes on a decidedly different approach to existing texts on electrophysiology, by considering electrical physiological processes from the viewpoint of electron flow, rather than the conventional notion of ion movement. It concisely describes the theoretical background of electron density and cellular voltage, before exploring thought-provoking questions such as the relationship between electrolyte distribution and transmembrane potential, and the source of electricity generation in living cells. A new theory of depolarisation and repolarisation is presented, and all topics of relevance ? such as the calcium/sodium/potassium problems, excitation-contraction coupling in muscles, and electrophysiology of organs and glands ? are comprehensively covered. Using plain language and well-chosen illustrations, the author has designed each chapter to provide a succinct overview of an individual topic in a format that appeals to both the expert and the uninitiated. Electron Flow in the Physiology of Living Cells proffers a refreshingly new way to understand a fascinatingly old subject.
Key Features
? Analyses electrical physiological functions as electricity (i.e. movement of electrons), which contrasts with the present teaching that these functions are phenomena indicating ion movement; it mirrors the classical work Electron Flow in Organic Chemistry (Paul H Scudder, 1992)
? Written by Professor Mark I M Noble, who holds three doctorates and four elected fellowships, and is an international authority on a number of subjects within the field of the science of the cardiovascular system
Introduction; Facts and Definitions; What about Volts?; What is the Current Idea about Cellular Voltage?; The Concept of Electron Density; Does the Electrolyte Distribution actually Determine the Trans-Membrane Electric Potential?; Where, within Living Cells, is Electricity Generated?; Depolarisation (Loss of Cytoplasmic Electron Density) Activation; A Test of the Impedance Hypothesis; Fast Depolarisation in Conducting Tissue, i.e., Muscle and Nerve Axons; Repolarisation; The Calcium, Sodium and Potassium Problems; Excitation-Contraction Coupling in Muscles; The Effect of the Ca2+ Problem on Cardiac Muscle Electrophysiology; Central and Autonomic Nervous Systems; Blood Vessels and Smooth Muscles; Electrophysiology of Endocrine Glands; Electrophysiology of Exocrine Glands; Exceptions from any General Model; Summary and General Comments
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