图书简介
During the last decade scientists in both basic and clinical research have renew ed their interest in the potential role of thrombolytic therapy in the treatment of acute ischemic stroke. The reevaluation of this approach was kindled by our growing knowledge of the pathogenesis of thrombotic and embolic stroke and by the development of new thrombolytic agents. With no proven therapy for acute ischemic stroke available, the potential value of early pharmacologic recanalization of occluded vessels in the management of acute stroke patients - an approach that has been supported by animal experiments and a limited number of uncontrolled clinical pilot studies - is again under scrutiny. A sym posium on ’Thrombolysis in Acute Cerebral Ischemia’ was held in Heidel berg, Germany, in May 1990 to summarize and discuss the pathophysiological background for thrombolysis in acute ischemic stroke and the recent ex perimental and clinical experience with the new generation of thrombolytic agents. The editors are fortunate to be able to include authoritative manuscripts from almost all the speakers at the symposium. These include reports of work by the most active investigators in this challenging field. The editors wish to express their gratitude to all the contributors for the additional work they have undertaken. Additionally, we would like to thank Springer-Verlag, Heidelberg, for its generous assistance in the preparation and rapid publication of this volume. Heidelberg, August 1990 WERNER HACKE GREGORY J. DEL ZopPO MATTHIAS HIRSCHBERG Contents I.
I. Acute Cerebral Ischemia and Thrombolysis.- Natural History of Atherothromboembolic Occlusion of Cerebral Arteries: Carotid Versus Vertebrobasilar Territories.- Fibrinolysis: Thrombolytic Agents, Mechanisms, and New Developments.- Fibrinolysis in Myocardial Infarction: Lessons for Cerebrovascular Disease.- Reperfusion of Ischemic Brain: Why and Why Not!.- Thrombolysis in Stroke: Timing of Recanalization and Its Clinical Consequences.- The Ischemic Penumbra: Fact or Fiction?.- Hemorrhagic Transformation in the Natural History of Acute Embolic Stroke.- Intracranial Hemorrhage After Coronary Thrombolysis with Tissue Plasminogen Activator.- Predictive Factors for the Effective Treatment of Acute Stroke with Intravenous Thrombolytic Agents.- Invasive Imaging Techniques in the Evaluation of Patient Selection and Cerebrovascular Recanalization.- The Role of Noninvasive Imaging Techniques in Cerebrovascular Recanalization.- II. Thrombolysis and Stroke Models.- Thrombolytic Therapy in Ischemic Stroke: Relevance and Limitations of Animal Models.- Update on Animal Model Experience with Recombinant Tissue Plasminogen Activator.- III. Clinical Trials.- Clinical Trials: Some General Considerations.- Intraarterial Urokinase Plasminogen Activator and Streptokinase in Carotid and Vertebrobasilar Territory Stroke: Clinical Outcome.- Fibrinolytic Recanalization Therapy in Acute Cerebrovascular Thromboembolism.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Thrombotic Stroke: Study Design, Recanalization, and Clinical Outcome.- Evaluation of Tissue Plasminogen Activator Early in the Course of Acute Ischemic Stroke.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Stroke.- Thrombolytic Therapy in Embolic and Thrombotic Cerebral Infarction: A Cooperative Study.- IV. Future Directions.- Problems in Formulating Therapeutic Trials.- Invasive and Noninvasive Vascular Imaging Techniques and Their Role in Clinical Stroke Trials.- Strategies for Early Treatment of Acute Cerebral Infarction.- V. Open Communications.- Topical Intraarterial Urokinase Infusion for Acute Stroke.- Local Thrombolytic Therapy in Acute Basilar Artery Occlusion: Experience with 18 Patients.- Vertebrobasilar Occlusion: Outcome With and Without Local Intraarterial Fibrinolysis.- Recanalization of Acute Middle Cerebral Artery Occlusion Monitored by Transcranial Doppler Sonography.- Neuropathological Findings After Thrombolytic Therapy in Acute Ischemic Stroke.- How Many Stroke Patients Are Candidates for Thrombolysis?.- Spontaneous Recanalization in Middle Cerebral Artery Occlusion.- In Vitro Thrombus Lysis by Urokinase in Preparation for Patient Studies.- Local Intraarterial Fibrinolysis in Acute Middle Cerebral Artery Occlusion.- Treatment of Acute Ischemic Stroke with Recombinant Tissue Plasminogen Activator: Evaluation with Regional Cerebral Blood Flow Single Photon Emission Computed Tomography.- Thrombolytic Therapy in Acute Ischemic Stroke: The Copenhagen Multicenter Study.- Thrombolytic Therapy in Cerebral Sinus Thrombosis: A Case Report.- Basilar Artery Occlusion Associated with Protein C Deficiency: Successful Treatment Using Recombinant Tissue Plasminogen Activator Infusion.- Intracerebral Hemorrhage and Infarction Volume Following Recombinant Tissue Plasminogen Activator in an Acute Stroke Model.- Prourokinase Therapy in Stroke.
Trade Policy 买家须知
- 关于产品：
- ● 正版保障：本网站隶属于中国国际图书贸易集团公司，确保所有图书都是100%正版。
- ● 环保纸张：进口图书大多使用的都是环保轻型张，颜色偏黄，重量比较轻。
- ● 毛边版：即书翻页的地方，故意做成了参差不齐的样子，一般为精装版，更具收藏价值。
关于退换货：- 由于预订产品的特殊性，采购订单正式发订后，买方不得无故取消全部或部分产品的订购。
- 由于进口图书的特殊性，发生以下情况的，请直接拒收货物，由快递返回：
- ● 外包装破损/发错货/少发货/图书外观破损/图书配件不全（例如：光盘等）
并请在工作日通过电话400-008-1110联系我们。
- 签收后，如发生以下情况，请在签收后的5个工作日内联系客服办理退换货：
- ● 缺页/错页/错印/脱线
关于发货时间：- 一般情况下：
- ●【现货】 下单后48小时内由北京（库房）发出快递。
- ●【预订】【预售】下单后国外发货，到货时间预计5-8周左右，店铺默认中通快递，如需顺丰快递邮费到付。
- ● 需要开具发票的客户，发货时间可能在上述基础上再延后1-2个工作日（紧急发票需求，请联系010-68433105/3213）；
- ● 如遇其他特殊原因，对发货时间有影响的，我们会第一时间在网站公告，敬请留意。
关于到货时间：- 由于进口图书入境入库后，都是委托第三方快递发货，所以我们只能保证在规定时间内发出，但无法为您保证确切的到货时间。
- ● 主要城市一般2-4天
- ● 偏远地区一般4-7天
关于接听咨询电话的时间：- 010-68433105/3213正常接听咨询电话的时间为：周一至周五上午8：30～下午5：00，周六、日及法定节假日休息，将无法接听来电，敬请谅解。
- 其它时间您也可以通过邮件联系我们：customer@readgo.cn,工作日会优先处理。
关于快递：- ● 已付款订单：主要由中通、宅急送负责派送，订单进度查询请拨打010-68433105/3213。
本书暂无推荐
本书暂无推荐
