图书简介
Modeling is fast becoming fundamental to understanding the processes that define biological systems. High-throughput technologies are producing increasing quantities of data that require an ever-expanding toolset for their effective analysis and interpretation. Analysis of high-throughput data in the context of a molecular interaction network is particularly informative as it has the potential to reveal the most relevant network modules with respect to a phenotype or biological process of interest.
Analysis of Biological Systems collects classical material on analysis, modeling and simulation, thereby acting as a unique point of reference. The joint application of statistical techniques to extract knowledge from big data and map it into mechanistic models is a current challenge of the field, and the reader will learn how to build and use models even if they have no computing or math background. An in-depth analysis of the currently available technologies, and a comparison between them, is also included. Unlike other reference books, this in-depth analysis is extended even to the field of language-based modeling. The overall result is an indispensable, self-contained and systematic approach to a rapidly expanding field of science.
Key Features:
○ The book jointly deals with static (statistical) and dynamic (simulation) technologies making it a strong reference for who wants to approach real systems biology problems
○ The content of the book is the result of more than ten years application of the material in university courses and to industrial-level problems in systems pharmacology and systems nutrition
○ There is no reference work available for the field of language-based modeling that is studied in depth in this book
Algorithmic Systems Biology; Setting the Context; Systems and Models; Static Modeling Technologies; Dynamic Modeling Technologies; Language-based Modeling; Dynamic Modeling Process; Simulation; Perspectives and Conclusions; Appendix A: Basic Math; Appendix B: Probability and Statistics; Appendix C: Semantics of Modeling Languages
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