图书简介
This book is a comprehensive guide on neural stem cell behavior in health and disease. It will cover the altered behavior of endogenous neural stem cells in neurodegenerative conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders.
First set of chapters will focus on neural stem cell proliferation, neuronal differentiation and maturation of progeny of cells derived from neural stem cells in brain regions, such as the hippocampus and the subventricular zone of the forebrain. Neural stem cell behavior in young and aged brains and functional implications of altered neural stem cell behavior will be discussed as well.
The second set of chapters will cover altered behavior of endogenous neural stem cells and their functional implications in disorders, such as temporal lobe epilepsy, cancer, traumatic brain injury, stroke, Alzheimer’s disease, addiction and alcohol use.
The third set of chapters will discuss prospects of stem cell therapy for various neurological disorders, which will comprise of their behavior after grafting and functional recovery mediated by them. Additional chapters will discuss how to generate the right neural cell types from induced pluripotent stem cells for screening and cell therapy of central nervous system disorders.
Key Features:
○ Breadth of information on neural stem cell behavior in health as well as disease and its implications
○ Inclusion of all recent advances in the field of neural stem cells
○ Focus on the therapeutic applications of stem cells for neurodegenerative disorders
Neural Stem Cells — Introduction; Neural Stem Cell Functions in the Adult Hippocampus; Neural Stem Cell Behavior in the Subventricular Zone of the Forebrain; Neural Stem Cells and Age – Related Neurodegeneration; Neural Stem Cell Response to Traumatic Brain Injury; Neural Stem Cell Behavior and Neurogenesis in Epilepsy; Neural Stem Cell Dysfunction after Cancer Therapy; Neural Stem Cell Behavior in Alzheimer’s Disease; Neural Stem Cells and Alcohol Use Disorders; Neural Stem Cell Behavior in Addiction; Vulnerability of Neural Stem Cells to Anaesthetic Agents; Induction of Neurogenesis from Astrocytes in Non – Neurogenic Regions of the Brain; Prospects of Neural Stem Cell Therapy for Alzheimer’s Disease; Lab to Clinic Translation of Stem Cell Therapy for Stroke; Neural Stem Cell Therapy for Parkinson’s Disease; Advances in Stem Cell Therapy for Temporal Lobe Epilepsy; Neural Stem Cell Therapy for Spinal Cord Injury; Generating the Right Neural Cell Types from Induced Pluripotent Stem Cells for Screening/Cell Therapy for CNS Disorders
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