图书简介

Contents; 1. Imaging life; Manfred Auer and Gary C. Howard; Part I: Imaging the Macromolecular Inventory; Structure and Mechanistic Function of the Building Blocks; Introduction to Section 1; Manfred Auer, Natalia Pinzon, and Gary Howard; 2. Protein crystallography and x-ray diffraction; John P. Rose, M. Gary Newton and Bi-Cheng Wang; 3. Magnetic resonance in structural biology; G. Marius Clore; 4. Cryo-electron microscopy; Phoebe Stewart; 5. Single-molecule imaging and force spectroscopy by atomic force microscopy; K. Tanuj Sapra and Daniel J. Muller; 6. Coherent x-ray diffraction imaging with free-electron lasers; Stefan Hau-Riege; Imaging Cellular and Tissue Architecture; How It All Fits Together to Sustain Life; Introduction to Section 2; Manfred Auer, Natalia Pinzon, and Gary Howard; 7. Bridging the resolution gap: Electron tomography and advanced three-dimensional SEM approaches for cellular volumes; Manfred Auer; 8. Correlated soft x-ray tomography and cryo-light microscopy; Elizabeth A. Smith, Bertrand P. Cinquin, Gerry McDermott, Mark A. Le Gros and Carolyn A. Larabell; 9. Breaking Abbe’s law: Super-accuracy and super-resolution fluorescence microscopy based on single molecule detection; Sethuramasundaram Pitchiaya, John R. Androsavich and Nils G. Walter; 10. Superresolution STED microscopy; Valentin Nagerl; 11. Imaging the (macro)molecular composition: Mass spectrometry imaging; Brendan Prideaux; 12. Non-destructive molecular mapping and imaging: Synchotron FTIR spectral imaging; Hoi-Ying Holman and Liang Chen; 13. Raman spectroscopic imaging of biological systems; Martin Schmidt, Pradeep N. Perera, Alexander Weber-Bargioni, Paul D. Adams, and P. James Schuck; 14. Automated microscopic imaging and survival statistics; Steven Finkbeiner; Modeling of Complex Biological Functions; Introduction to Section 3; Manfred Auer, Natalia Pinzon, and Gary Howard; 15. From voxel maps to models; Chandrajit Bajaj; 16. Building and using 3D digital atlases of complex model animals at single-cell resolution; Hanchuan Peng; Conclusions; 17. Quo vadis, imaging; Manfred Auer and Gary C. Howard

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